Our major interest is in how plants utilize signaling molecules, known as inositol pyrophosphates, to sense and respond to their environment. We are able to delineate the roles of these signaling molecules by studying Arabidopsis thaliana mutants and overexpressors for enzymes in the inositol phosphate synthetic pathway. Our transgenics also reveal interesting impacts of the inositol phosphates on various stress responses as well as plant physiology.